Wednesday, February 13, 2013

Feet Of Flames: These Survival Boots Include a Built-In Fire Starting Kit

RockS2V is working hard to build a name for itself when it comes to emergency survival gear. The company's Provision coat includes a built-in life-saving toolkit if you find yourself stranded somewhere remote, and its new Substratum boots feature a secret compartment inside designed to stash an emergency fire starting kit. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/d67gCs2X8Oo/feet-of-flames-these-survival-boots-include-a-built+in-fire-starting-kit

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Latin America would like a Latin pope, odds slim

MEXICO CITY (AP) ? Latin America is home to the world's biggest Roman Catholic population, but chances seem slim that the next pope will come from the region.

Names of high-ranking churchmen from Latin American countries have been bandied about, but most members of the College of Cardinals are from Europe.

The college will elect a successor for the 85-year-old Pope Benedict VXI, who announced Monday he will resign because of age.

Brazilian Cardinals Joao Braz de Aviz and Odilo Pedro Scherer, and Argentines Leonardo Sandri and Jorge Mario Bergoglio have been mentioned as possible contenders.

About 40 percent of the world's Catholics live in Latin America. But the church also faces challenges from evangelical faiths in the region.

Source: http://news.yahoo.com/latin-america-latin-pope-odds-slim-000337269.html

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Innovative technique pinpoints protein locations, helping scientists figure out their functions

Feb. 12, 2013 ? An innovative technique which pinpoints protein locations and helps researchers unravel the protein's functions has been developed by the researchers from the Massachusetts Institute of Technology (MIT), researchers who recently moved from MIT to the Ulsan National Institute of Science (UNIST) explain.

Scientist from MIT have now developed a technique that can tag all of the proteins in a particular region of a cell, allowing them to more accurately map those proteins.

"There was no previous high-quality map of the matrix subdomain of mitochondria, and now we have one" said Alice Ting, the Ellen Swallow Richards Associate Professor of Chemistry at MIT. "We're still really far from that goal, but the overarching motivation is to get closer to that goal."

This innovative technique combines the strengths of two existing techniques -- microscopic imaging and mass spectrometry -- to map proteins in a specific cell location and generate a comprehensive list of all the proteins in that area.

In a paper appearing in the Jan. 31 online edition of Science, Rhee and colleagues used the new technique to identify nearly 500 proteins located in the mitochondrial matrix -- the innermost compartment found in mitochondria, which can be thought of as the power houses of the cell where energy is generated. Previous attempts to map the entire set of proteins in the matrix (proteome) yielded a list of only 37 proteins.

Protein labeling

To demonstrate the technique's power, the researchers created a comprehensive list of the proteins found in the mitochondrial matrix. Most of a cell's energy generation takes place in mitochondria, as well as many biosynthetic processes.

Using the new method, the team increased the number of proteins known to be located in the mitochondrial matrix. "There was no previous high-quality map of the matrix subdomain of mitochondria, and now we have one," says Ting, adding that this new wealth of information should help biologists to learn more about the functions of many of those proteins.

Already, the team has found that an enzyme called ppox -- involved in synthesizing heme, the iron-porphyrin complex found in hemoglobin -- is not located where biologists had thought it was. As heme precursors move through the biosynthetic pathway, they are shuttled to different parts of the cell. Finding that ppox is in the matrix means that there must be unknown transporter proteins bringing heme precursors into the matrix, Ting says.

The researchers are now investigating proteins found in another compartment of the mitochondria, the intermembrane space. They are also modifying the chemistry of the labeling system so they can use it for other tasks such as mapping the topology of membrane proteins and detecting specific protein-protein interactions.

The lead scientists of this research are Hyun-Woo Rhee (former MIT postdoc, currently Assistant Professor, School of Nano-Bioscience and Chemical Engineering, UNIST) and Peng Zou, who received a PhD from MIT in 2012.

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The above story is reprinted from materials provided by UNIST (Ulsan National Institute of Science and Technology).

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. H.-W. Rhee, P. Zou, N. D. Udeshi, J. D. Martell, V. K. Mootha, S. A. Carr, A. Y. Ting. Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging. Science, 2013; DOI: 10.1126/science.1230593

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/biochemistry/~3/ZEeORaoJE3U/130212210009.htm

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Thieves steal heat pumps from Arnold church

An Anne Arundel County church is out tens of thousands of dollars after police said thieves stole four of its heat pumps.

Police said someone stole the four heat pumps from Gloria Dei Lutheran Church in Arnold about two weeks ago by cutting the wires and piping from the back of the building, loading them into a truck and driving off.

Click to read more.

Source: http://www.nbcnews.com/id/50782000/ns/local_news-baltimore_md/

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Apple CEO: Shareholder lawsuit is 'silly sideshow'

FILE - In this Wednesday, March 7, 2012 photo, Apple CEO Tim Cook announces the new iPad in San Francisco. Apple CEO Tim Cook is calling a shareholder lawsuit against the company a "silly sideshow,"on Tuesday, Feb. 12, 2013, even as he said he is open to looking at the shareholder's proposals for sharing more cash with investors. (AP Photo/Paul Sakuma, File)

FILE - In this Wednesday, March 7, 2012 photo, Apple CEO Tim Cook announces the new iPad in San Francisco. Apple CEO Tim Cook is calling a shareholder lawsuit against the company a "silly sideshow,"on Tuesday, Feb. 12, 2013, even as he said he is open to looking at the shareholder's proposals for sharing more cash with investors. (AP Photo/Paul Sakuma, File)

Apple CEO Tim Cook is calling a shareholder lawsuit against the company a "silly sideshow," even as he said he is open to looking at the shareholder's proposals for sharing more cash with investors.

Investor David Einhorn sued Apple Inc. last week, saying a proposal slated for a vote at the company's annual meeting in two weeks would make it more difficult to enact his plan to reward shareholders by distributing a new class of shares.

Cook said Apple's proposal puts more power in the hands of shareholders, making it difficult to understand why a shareholder would fight it. Calling the fight a waste of time, Cook said Apple won't waste money by mailing shareholders to persuade them to vote for the proposal.

"My preference is that everyone on both sides of this issue would take the money they're spending on this and donating it to a worthy cause," Cook said.

Repeating previous statements, Cook also said that the company is "seriously" looking at ways to hand out more cash to shareholders.

Investors appeared to be listening for something more substantive out of Cook on the cash issue. Apple's stock fell $7.40, or 1.5 percent, to $472.53 in afternoon trading after his morning speech at a Goldman Sachs investor conference in San Francisco.

The stock market has hammered Apple's stock since the September launch of the iPhone 5. The company's growth, which has been rapid for nearly a decade, is slowing drastically in the absence of a new groundbreaking product. Wall Street is clamoring for Apple to share more of its cash, which amounted to $137 billion at the end of last year and is still growing fast because of the company's massive profits.

Companies normally don't sit on that much cash, as it's not very productive. They prefer to invest it in their business or give it to shareholders. Einhorn said Apple's cash hoard is a symptom of a defensive, "Depression-era mentality."

Cook rebuted that assertion Tuesday, saying the company invested $10 billion in its business last year, through spending on research and design, equipment and an expansion of its chain of stores. It has also committed to handing out $45 billion to shareholders over three years, through dividends and share buybacks.

Analysts, however, point out that Apple seems to have run out of things to invest in, and the $45 billion commitment is small compared with the company's profits.

Goldman analyst Bill Shope asked Cook about two other hot-button issues: whether Apple would make a cheaper phone and one with a larger screen, both of which rivals have been doing using Google's Android operating system. Cook was as usual evasive about Apple's product plans, preferring to point out that it sells older iPhone models at a reduced price and that there's more to the experience of a screen than its size.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-02-12-Apple-CEO/id-92ed9575670f45fb988050a01a893db1

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Sunday, February 10, 2013

Benutzer:MatsumotoBosley316 ? Hilfe_ProMan

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Just about everyone is using the internet for numerous purposes and cause. One of the many explanations why people use the internet is to make money. Earning money online is an excellent endeavor because you do not need to go somewhere else to work as well as earn cash. You will find truly a lot of opportunities available and below are some of the best online business ideas.

Affiliate Marketing Business This particular idea involves marketing other people's or other company's services by yourself blog or website. Essentially, you are going to earn through commissions from each and every successful sale. You will need to become very good in promoting, as if you google top 10 are an offline sales person. Some other skills essential to allow it to be big in affiliate marketing are web marketing, sales copywriting, and so on Affiliate products and services you have to select are those which are in line with your own passions and interests. Don't just select those that are quite popular, tend to be achievement what you want.

Blogging Business In essence, the blog is really a website whose contents might be articles or even reviews organized chronologically just like you were placing daily entries in your diary. You can also add photos and movies. If you have a blog, there are numerous online business methods you could earn money. You will find paid ads you can make an application for. Ads will be displayed on your weblogs; ads that are in relation to the contents of the page. You may also earn through affiliate marketing with creating content. You can write reviews or articles about the products you might be affiliated in order to; and proving links that visitors can follow where the affiliate products and services may be purchased. You have to be skilled at copy writing, web marketing and social networking in order to thrive in this business.

Online Auctions Many websites like Amazon . com and eBay are ideal places where sale are held. You are able to sell and resell items through these online areas. Drop shipping services can also be implemented when you organized your auction business. You have to be proficient at sales copywriting and merchandising to really make it within this endeavor. In addition, you should also be able to provide excellent customer support so you will gain loyal patronage from online purchasers.

Online Shop You can also put up your personal online shop wherein you are able to perform e-commerce. You are able to sell numerous products and also offer technology-based services on your web site. You have to get the skills of an excellent entrepreneur to really make it excellent in this endeavor.

Arts And Crafts Company If you have a good artistic hobby such as knitting, painting or sculpting, this is a company that you could certainly consider. Simply create your works of art and sell them online. You are able to handcraft clothes, jewelries, bags and more. You may also cook cookies, cupcakes along with other pastries. You will discover there are actually websites and businesses who hire or pay people for making crafts as well as arts for them. Aside from your creative skills, you should also try to become good at selling as well as marketing in order to generate high sales for the business.

Source: http://www.proman-help.isys-informatik.ch/index.php/Benutzer%3AMatsumotoBosley316

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